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Moreover, in facing various pathological challenges, the mammalian heart, which possesses high levels of mitochondria and weak antioxidant capacity, is susceptible to oxidant production and oxidative damage

Graves Disease, an autoimmune disorder, can cause hyperthyroidism and lead to serious complications if not properly treated

S., Vargas, C

2A) in order to increase the expression of genes without inducing a double-stranded DNA breaka process known as CRISPR-mediated activation (CRISPRa) [65,66,67] (Fig